Protein Info for RR42_RS24570 in Cupriavidus basilensis FW507-4G11

Annotation: alpha/beta hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 325 PF00135: COesterase" amino acids 77 to 186 (110 residues), 35.3 bits, see alignment E=1.3e-12 PF20434: BD-FAE" amino acids 88 to 181 (94 residues), 77.4 bits, see alignment E=2.5e-25 PF07859: Abhydrolase_3" amino acids 94 to 298 (205 residues), 199.1 bits, see alignment E=1.6e-62

Best Hits

KEGG orthology group: None (inferred from 93% identity to rpi:Rpic_4321)

Predicted SEED Role

"Esterase/lipase/thioesterase( EC:3.1.1.1 )"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YA53 at UniProt or InterPro

Protein Sequence (325 amino acids)

>RR42_RS24570 alpha/beta hydrolase (Cupriavidus basilensis FW507-4G11)
MSSELSWQPLSEVAEDARPMVQAFREAGGLHYGSQAPEPSRANFARACGLHGLKDIDGVD
HRDIMVPVTDGEIRVRLYQPDEAECAGGKGPLAVFLHGGGWVIGSIDTHDGICRLLARQS
GCIVASVEYRLAPEHQWPVPLRDCEQALGYLVANAAALSIDASRVVLAGDSAGGSMATII
SNAPATGAYQVVGQVLLYPVTDLTASRPSYGRFQGGLPLVAESMQWFRDLYVPAGTPLDQ
PALSPLLHAEGRRQPPMFITTVGLDPLCDEGIEYAAMAARAGGLLEHHHLPRHMHGIFTA
AGRISTAQNLLERAGLFIRRLSSHS