Protein Info for RR42_RS22610 in Cupriavidus basilensis FW507-4G11

Annotation: toxin HipA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 444 TIGR03071: HipA N-terminal domain" amino acids 10 to 109 (100 residues), 83.7 bits, see alignment E=4.2e-28 PF13657: Couple_hipA" amino acids 10 to 109 (100 residues), 83.3 bits, see alignment E=1.5e-27 PF07804: HipA_C" amino acids 156 to 404 (249 residues), 174.3 bits, see alignment E=2.9e-55

Best Hits

KEGG orthology group: K07154, (no description) (inferred from 66% identity to gca:Galf_0974)

Predicted SEED Role

"HipA protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YJA4 at UniProt or InterPro

Protein Sequence (444 amino acids)

>RR42_RS22610 toxin HipA (Cupriavidus basilensis FW507-4G11)
MGRRSHKQRLQIWMNGVPVGIWERAQVESLTYFDEWIQDEQGRPLSLSLPFLPANASYKG
RIVTDFFDNLLPDSDAIRRRLAQRYRTGGVTPFELLAVLGRDCVGALQLLEEGDVPADLT
TINGRPLSEAQVARVLRDTTSAAPLGAYDGDDELRLSIAGAQEKTALLHHQGQWMLPHGS
TPTTHIFKLPLGMVGNMRADMRTSVENEWLCAQIVAGYGLPVARCDIARFEDQKALIVER
FDRRRASDGRWIVRLPQEDLCQATGTPALLKYQADGGPGMTALMNMLAGSEQAEADRRNF
FKAQLVFWLLAATDGHAKNFSIALLPRGSYRSTPLYDVLSAHPIIGPGRNQVAPQKAKLA
MAVRGNENYYLIGQIRRRHWLAQGRQVGLSKESVEALIQELIAATDLVLSTVAASLPAGF
PADLAAAILDGVRRQSRKLAGMPA