Protein Info for RR42_RS21185 in Cupriavidus basilensis FW507-4G11

Annotation: AMP nucleosidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 498 TIGR01717: AMP nucleosidase" amino acids 25 to 498 (474 residues), 633.9 bits, see alignment E=9.1e-195 PF10423: AMNp_N" amino acids 26 to 178 (153 residues), 163.3 bits, see alignment E=3.4e-52 PF01048: PNP_UDP_1" amino acids 285 to 445 (161 residues), 68.8 bits, see alignment E=4.9e-23

Best Hits

KEGG orthology group: K01241, AMP nucleosidase [EC: 3.2.2.4] (inferred from 92% identity to cti:RALTA_B0070)

Predicted SEED Role

"AMP nucleosidase (EC 3.2.2.4)" in subsystem Purine conversions (EC 3.2.2.4)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.2.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YG54 at UniProt or InterPro

Protein Sequence (498 amino acids)

>RR42_RS21185 AMP nucleosidase (Cupriavidus basilensis FW507-4G11)
MFPMNASIFSSAHPADQLAEFSDADAALARIREIYDASVGAIRARFDAFAQGQPLPSAAH
ACYPYLGISVNLETMVTDSRPSWGTVAYPGVYGTTVTRPELLADYYRDQIERLIRYHRVP
VVVGVSRRPIPLPFVIEASTTDISYTQARELEASFVLPELSRIDDAIANGTYEPVPGEAW
PLSMFPGERVDLALQRLYHYTGTAPQHFQRFVLFTNYQRYVDEFIALGRSLMAAEDAQGA
DGYARFVEPGDVVQERGEAEPDDALRPRALPQMPAYHLVREDKLGVTLVNIGVGPSNAKT
MTDHLAVLRPHCWLMVGHCGGLRRSQQLGDYVLAHAYVRDDHVLDHDLPPWVPVPPIAEI
QVALQEAVVRVTGLSGNEMKTRMRTGTVVSTDDRNWELKSKALYARFNQSRAIAIDMESA
TVAANGFRLRVPYGTLLCVSDKPLHGELKLRGMANAFYRQRVSQHMSIGLEAIRILREGG
AEQLHSRKLRSFDEPAFR