Protein Info for RR42_RS20525 in Cupriavidus basilensis FW507-4G11

Annotation: LuxR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 222 PF00072: Response_reg" amino acids 8 to 123 (116 residues), 87.7 bits, see alignment E=6.2e-29 PF00196: GerE" amino acids 153 to 208 (56 residues), 60.2 bits, see alignment E=1.2e-20

Best Hits

Swiss-Prot: 35% identical to DEVR_MYCTO: DNA-binding transcriptional activator DevR/DosR (devR) from Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

KEGG orthology group: None (inferred from 86% identity to reh:H16_A3710)

Predicted SEED Role

"DNA-binding response regulator, LuxR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YFJ7 at UniProt or InterPro

Protein Sequence (222 amino acids)

>RR42_RS20525 LuxR family transcriptional regulator (Cupriavidus basilensis FW507-4G11)
MTSAPARVLLIDDHALVRDGMRMRLALQPELAVVGEADDGEAALAWLARASAEQMPELVI
TDIGMRGMGGIALAAALHEDYPELAVLIVSMHDNLEYVRQAIRAGARGYVLKDAPADELM
AAIAAVLAGRVFYSARIARSMAEQSPAAGPLDALTPRERDIFNCIGRGQANKDIAAALGV
SVRTIETHRLNLRRKLGIEGRAELVKFAVEQGSTEGGPAGSQ