Protein Info for RR42_RS20250 in Cupriavidus basilensis FW507-4G11

Annotation: branched-chain amino acid ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 383 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF13458: Peripla_BP_6" amino acids 24 to 369 (346 residues), 174.1 bits, see alignment E=1e-54 PF13433: Peripla_BP_5" amino acids 25 to 237 (213 residues), 39.4 bits, see alignment E=6.2e-14 PF01094: ANF_receptor" amino acids 56 to 224 (169 residues), 73.6 bits, see alignment E=2.3e-24

Best Hits

KEGG orthology group: K01999, branched-chain amino acid transport system substrate-binding protein (inferred from 92% identity to cti:RALTA_A3110)

Predicted SEED Role

"Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YLG5 at UniProt or InterPro

Protein Sequence (383 amino acids)

>RR42_RS20250 branched-chain amino acid ABC transporter substrate-binding protein (Cupriavidus basilensis FW507-4G11)
MTFKRASLLALAAASLCAGTASAQVKVGVTLSATGPAASLGIPEKNTISLLPKEIAGKKI
EYIVLDDASDTTTAVKNTRKLISEDKVDVIVGSTVTPNSLAMVDVVAENDTPMITLAASA
RIIEPMDAKRAWVFKTPQNDSHMATAIAEHMTNHNVKTVAFIGFADAYGDSWAQEFAKVG
EMRKIKVVANERFARTDTSVTGQVLKMMGTNPDAVLIAGSGTPAALPAKALKERGWKGKI
YQTHGVANADFLRVCGKDCEGTFLPAGPLLVAEQLPDTNPVKKPAITYKTAYEKAFGGQV
STFGGHAWDAGLLLQRAIPEALKKGQPGTKEFRKALRDAMEQTKELPISHGIMNMTPTDH
LGLDQRARVMVEIVDGKWKLQTK