Protein Info for RR42_RS19840 in Cupriavidus basilensis FW507-4G11

Annotation: amidohydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 403 TIGR01891: amidohydrolase" amino acids 28 to 389 (362 residues), 326.6 bits, see alignment E=1e-101 PF01546: Peptidase_M20" amino acids 86 to 398 (313 residues), 158.7 bits, see alignment E=1.9e-50 PF07687: M20_dimer" amino acids 200 to 290 (91 residues), 45.5 bits, see alignment E=6.4e-16

Best Hits

KEGG orthology group: K01451, hippurate hydrolase [EC: 3.5.1.32] (inferred from 91% identity to reu:Reut_A3289)

Predicted SEED Role

"Metal-dependent amidase/aminoacylase/carboxypeptidase"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.32

Use Curated BLAST to search for 3.5.1.32

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y7I3 at UniProt or InterPro

Protein Sequence (403 amino acids)

>RR42_RS19840 amidohydrolase (Cupriavidus basilensis FW507-4G11)
MTREPTLTPFQLLPHLLPAIQIDAETFIGIRRQIHAQPELGFEVGATSKLVATLLESWGY
EVHTGIGKSGVVGQLKLGNGKRRLGIRADMDALPVVEATGLPYASKIPGKMHACGHDGHT
AILLAAAKALADSRDFDGTLNLIFQPDEENLCGARAMIEDGLFARFPCDAVFALHNMPGV
PAGTFRVLPGPVSLSSDVADVTIKGVGGHGAMPHRARDPIAASAAIVTALQTVVARNVAP
DDTAVVSVGFIRGGATHNVIPESVTLGLNVRAARPETRALVEQRIREIVSLTAQAHGVEA
HIDYRQLTPPMVNTQAETTLAQQVCAELVGTDKVVTQAPKGLNGSEDFAWMLNEVPGCYL
ILGNGEGEFGGCMVHNPGYDFNDRVLPLGAACWVRLAQTYLAG