Protein Info for RR42_RS19475 in Cupriavidus basilensis FW507-4G11

Annotation: general secretion pathway protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 199 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details PF11356: T2SSC" amino acids 76 to 138 (63 residues), 27.9 bits, see alignment E=9.5e-11

Best Hits

KEGG orthology group: K02452, general secretion pathway protein C (inferred from 69% identity to reh:H16_A3532)

Predicted SEED Role

"General secretion pathway protein C"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y7C0 at UniProt or InterPro

Protein Sequence (199 amino acids)

>RR42_RS19475 general secretion pathway protein (Cupriavidus basilensis FW507-4G11)
MRPALRFNPSSLWLPRLAALVLFVALCALATRWALTFSAMQTIAVPNAARVAQTEAVETG
AAGTLFGGNAQSGVRDVQLIGVVADIGSGAGAAIVSLDGGPAKAVRAGTALSPQIRLTEV
RDRGVVIERNGVRQEIALPVPAIVTRGPAAATQPALPAGAAAPLSTPMPVPATPIPAPPP
QSLPQQQSQGGNEPISAKD