Protein Info for RR42_RS18900 in Cupriavidus basilensis FW507-4G11

Annotation: membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 207 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 38 to 57 (20 residues), see Phobius details amino acids 64 to 87 (24 residues), see Phobius details amino acids 108 to 133 (26 residues), see Phobius details amino acids 139 to 160 (22 residues), see Phobius details amino acids 181 to 202 (22 residues), see Phobius details TIGR00427: membrane protein, MarC family" amino acids 4 to 198 (195 residues), 197.4 bits, see alignment E=1.1e-62 PF01914: MarC" amino acids 4 to 201 (198 residues), 198.5 bits, see alignment E=4.3e-63

Best Hits

Swiss-Prot: 39% identical to Y267_BUCAI: UPF0056 membrane protein BU267 (BU267) from Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)

KEGG orthology group: K05595, multiple antibiotic resistance protein (inferred from 92% identity to reu:Reut_A3108)

Predicted SEED Role

"Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)" in subsystem Histidine Biosynthesis (EC 2.4.2.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.2.-

Use Curated BLAST to search for 2.4.2.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y730 at UniProt or InterPro

Protein Sequence (207 amino acids)

>RR42_RS18900 membrane protein (Cupriavidus basilensis FW507-4G11)
MDTLKSFISLLALINPIGAIPFFISLTTQQTEEEKRHTIKIASISVATVVGISALLGQQI
IEFFNISVASLQVGGGLIMIMMAMNMLNAQTSRTKATPEEEDEAEAKASIAVVPLALPLL
TGPGSISTVIVYAGKTQHWYQLLILVGIGIALGAVVYIVFRAADPIARVIGRTGINIGTR
LMGLILSALAVEFIVDGLKTLLPVLKS