Protein Info for RR42_RS17770 in Cupriavidus basilensis FW507-4G11

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 745 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF07715: Plug" amino acids 66 to 164 (99 residues), 83.6 bits, see alignment E=1.4e-27 TIGR01783: TonB-dependent siderophore receptor" amino acids 68 to 741 (674 residues), 299.4 bits, see alignment E=3e-93 PF00593: TonB_dep_Rec" amino acids 248 to 712 (465 residues), 178.7 bits, see alignment E=4e-56

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 78% identity to rme:Rmet_3077)

Predicted SEED Role

"Ferrichrome-iron receptor" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y6B9 at UniProt or InterPro

Protein Sequence (745 amino acids)

>RR42_RS17770 TonB-dependent receptor (Cupriavidus basilensis FW507-4G11)
MNRRTPIATALLALFATPVAALAQTAATAPATQPTTTLHEVVVQGSSVNDDYNAVKNAIS
KLPAELRDIPQSVTVVNKALIDAQGGTSLADALRNVPGITIGGAEGGQIGNNINLNGFSA
RTDIYLDGFRDRGQYYRDVFALDSVEVLMGPSSMLFGRGSTGGVINQVTKKPSLKAATEV
TGSVTTNGLVRATADYNTPTGETSAFRIAAMAQDGSASTRDQTKVKDFGLAPSWRLGIGT
PTEITLSALLQHNEDQPDYGLPAINGHPVNVDRKTAYGFNDDRTIQDVAALGATVDHKFS
PNLRLRNQTQFNYVNTNARETAPNAVGTVSAKGFTPLTTTTLPLDALFVRQQSHDRHIRD
YSIFNQTELTAKFDTGPVKHTVLVGAEIGHDGYDNQNYYRNGTCNGVPLNSAATPTAAAG
ISGYAACEPVVNPTYSNSPATAPSATGNRQGAAANTLAAYINDSVEFSKQWKLVGGLRYD
KYIASITNSINSSNTLGSTVLPSASQTVNFTSVRVGGIWQPTEAQSYYLSYGTSFNPSLE
QLVGTVGQQNLDPEKNKSYEVGGKWDLLGGDLSLNSALFQITKDNARSQIDATTYSLAGK
IRVRGFRAGATGRITSKWQVFAGYTYLDGEIVNGIAAGTQGMVPTNTPKHTATAWTSYRV
LQDWEVGGGAFYMSQRYANNTNTVQVGGYVRWDGMIAYHQPKYDVRLNLFNVFDKKYYDA
LIQSDGGRSVPGTGRTAMLSFIYRM