Protein Info for RR42_RS16965 in Cupriavidus basilensis FW507-4G11

Annotation: ABC transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 258 PF00005: ABC_tran" amino acids 23 to 184 (162 residues), 111.8 bits, see alignment E=6.3e-36 PF12399: BCA_ABC_TP_C" amino acids 232 to 257 (26 residues), 45.6 bits, see alignment (E = 6.2e-16)

Best Hits

Swiss-Prot: 48% identical to LIVG_SHIFL: High-affinity branched-chain amino acid transport ATP-binding protein LivG (livG) from Shigella flexneri

KEGG orthology group: K01995, branched-chain amino acid transport system ATP-binding protein (inferred from 92% identity to reh:H16_A3027)

MetaCyc: 48% identical to branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivG (Escherichia coli K-12 substr. MG1655)
ABC-15-RXN [EC: 7.4.2.2]; 7.4.2.2 [EC: 7.4.2.2]; 7.4.2.2 [EC: 7.4.2.2]; 7.4.2.2 [EC: 7.4.2.2]

Predicted SEED Role

"Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1)" in subsystem ABC transporter branched-chain amino acid (TC 3.A.1.4.1) (TC 3.A.1.4.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YFR0 at UniProt or InterPro

Protein Sequence (258 amino acids)

>RR42_RS16965 ABC transporter (Cupriavidus basilensis FW507-4G11)
MSNENLLLSVQGVNKRFGGLQALSDVGLQIKPGEIYGLIGPNGAGKTTFFNVITGLYTPD
SGEFVLGGKAYQPTAVHEVAKAGIARTFQNIRLFGEMTALENVMVGRHVRTKAGLFGAVF
RPPSVRREEHSVEDWAHDLLEYVGIGKYAHFTSRNLSYGHQRRLEIARALATEPKLLALD
EPAAGMNATEKVELRGLLDKIRSDGKTILLIEHDVKLVMGLCNRLTVLDYGKVIAQGLPH
EVQSNPAVIEAYLGTPAH