Protein Info for RR42_RS16860 in Cupriavidus basilensis FW507-4G11

Annotation: pilus assembly protein PilE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 142 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details PF07963: N_methyl" amino acids 10 to 33 (24 residues), 34.9 bits, see alignment 7.9e-13 TIGR02532: prepilin-type N-terminal cleavage/methylation domain" amino acids 11 to 33 (23 residues), 34.8 bits, see alignment 4.8e-13 PF16732: ComP_DUS" amino acids 34 to 124 (91 residues), 74.1 bits, see alignment E=1.4e-24

Best Hits

KEGG orthology group: K02655, type IV pilus assembly protein PilE (inferred from 64% identity to reu:Reut_A0399)

Predicted SEED Role

"Type IV pilus biogenesis protein PilE" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YD23 at UniProt or InterPro

Protein Sequence (142 amino acids)

>RR42_RS16860 pilus assembly protein PilE (Cupriavidus basilensis FW507-4G11)
MGCDRRARLEAGFTLIELMVTVAIIAILASVAYPSYLQYVVRSNRVAAESFLLEVSSMQE
RYLVDNRAYASSLATLGYASLPATVSPNYQITVAVVAGPPPGYVLSATPQGGQATNDTAC
GTLTLSGNGDKSASGGSLNCWK