Protein Info for RR42_RS16820 in Cupriavidus basilensis FW507-4G11

Annotation: fatty-acid--CoA ligase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 519 PF00501: AMP-binding" amino acids 8 to 375 (368 residues), 284 bits, see alignment E=1.7e-88 PF13193: AMP-binding_C" amino acids 425 to 500 (76 residues), 68.7 bits, see alignment E=6.8e-23

Best Hits

KEGG orthology group: None (inferred from 77% identity to vpe:Varpa_2252)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YFN1 at UniProt or InterPro

Protein Sequence (519 amino acids)

>RR42_RS16820 fatty-acid--CoA ligase (Cupriavidus basilensis FW507-4G11)
MYLTQALHRAVQQHPERIAVRYGERQRSFRQLAERVARLAGALRKLGMQSGDRVAMLSLN
SDRFLEYQMAVPWAGGVLNPCNTRWSAAEILYSLDDSGSTILLVDETFRALAVQLRRDAA
TLRELIYCGDGEVPAGMHGYEALLANAAPVPDAVRRDEDLAGIFYTGGTTGFPKGVMLSH
ANLCASGLALRAEGLATPGGTYLHAAPMFHLADMGLAMPQWMEGNTHAIIPAFNPELVLD
TLERDRVTHMLLVPTMIQMMVDHPAMKKPRDLSALQAIFYGASPISEAVLERAMAALPGV
GFVQAYGMTELSPLATINPAWYHTAEGRAQGKLRAAGRASYTSEVRIVDGEGREVPRGTV
GEVAVRGPTVMQGYWNKPEQTAAAVRDGWMHTGDGGYMDEDGFIFIVDRLKDMIVSGGEN
VYSAEVENALALHPAVVASAVIGVPSAEWGEAVHAVVVGRPGTSATAGELIDHCKTLIAG
YKCPRSVEFRDALPLSGAGKILKIELRKPFWEGQQRQVG