Protein Info for RR42_RS16035 in Cupriavidus basilensis FW507-4G11

Annotation: gramicidin biosynthesis protein GrsT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1362 transmembrane" amino acids 30 to 53 (24 residues), see Phobius details PF04357: TamB" amino acids 977 to 1322 (346 residues), 208.5 bits, see alignment E=9.8e-66

Best Hits

KEGG orthology group: K09800, hypothetical protein (inferred from 71% identity to reh:H16_A2955)

Predicted SEED Role

"tRNA(Ile)-lysidine synthetase (EC 6.3.4.19)" (EC 6.3.4.19)

Isozymes

Compare fitness of predicted isozymes for: 6.3.4.19

Use Curated BLAST to search for 6.3.4.19

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YCY9 at UniProt or InterPro

Protein Sequence (1362 amino acids)

>RR42_RS16035 gramicidin biosynthesis protein GrsT (Cupriavidus basilensis FW507-4G11)
MSIPDMPPVPASGEVPPGPARPRRTRLGRWLAWCVVVVLLLVLAAVAAVVLALRTEAGTR
QLWSLATHLSSGALSGKLEGGTVAHGLRLRDVVFATGETRVTIDRVDGNWALGWSPTRLH
VSALRVGAVTLRLAPSQPDNAPASLPRSLDLPLAVDVDTLTLDRLTLLQGPPATPSEMVF
SDLAGSLHSDGQRHRLSVERLVTPYGKLAANAQIAGQAPFALNGAALLEGSWQKESFSIS
ANVRGSLAMLHAQAEASGDRLRGRAEADLTPFGKVPFTHVLVNGEHINPRLFSASAPRAN
LSVQAELRPVDGAATPAQATPASAPAAKPGSAHDSAPLRVAGDVRIVNHEAGKLDAERLP
VESVQAHIEVSEAAQMVRDLQVALAGGGEIRGGGALRDGRGGFDLDVRNLDPQALYGSLK
RVRLSGPVSLRMEPGRKSVALDLAGGEYKLFADAHLDGEAVTLTSLRAGIGAGTLNADGK
LSLKDAQPFSFKGKLINFDPARVAEVAPGRINAEFTASGTLAPEHRVALDFAVRDSVYAG
LPMRGEGKLRLAGERLLPSQATLEMAGNQAQINGSFGARGDRLKVHVDAPQLDRLKFGVA
GVLKLDADVTGTLARPEIVASYDAQSLVVGPHHVASASGSAELRGGLNGTLALKLHARDY
RGPVATLRTLDASLSGTQASHAFDLKVAGALHDKPMQLALSGQGAWQGAAGWKGTIGTLE
ERGTVNVRLIAPTQLQVADQRVHLGAASLQFERARVTVDSFEFDHGRIRTQGNLDGLQVA
NLLRLAEALTGEAPPVRSDLVLDGRWNITLAESASGFAELRRRSGDVSVSAGRGYTALGL
GETALRAEFAGSRVNLKGGIEAARVGKVVVDASAGLIQEQGLMTVTPASTLAGKVSLDVP
KIKSLEALSGPQYAFDGKLAAVLQLAGSVGQPLLTGTIDGTGIAITLYDLGIQLTDGIVH
VVLDQNTIELKQVEFRGGDGKIVATGNVKLGETDPNLTGKIVADKLQLFASPERTLIISG
DASIANENRQIVIRGKFRVDRGLFDLPKAGAPELGDDVVVVRRRDQREIKTAATPLPEAR
PASRFSPLIDLTLDLGDNFRFRGAGADLRLNGQLGVRSAPLTPLRATGTIRVTDGTYEAF
GRKLNIERGIVNFNGPVDNPNLNIRAMRRNQEVEAGVEVTGTVRLPRVKLVSEPNVPEED
KLSWLMFGYGAESAAAGQQQQLSAGALGGAALGMLGGRAGKGIVQHLGIDEFSIGPSAAG
LNDQQVVSVGKAVTEKISVGYEQSLTSASNVVKLTWAFSRRWSLIAKGGSINGLSVLFNR
RFDSWGNLFTGASGRAGTARSQTDASQDADSNATDAAAPAQP