Protein Info for RR42_RS15870 in Cupriavidus basilensis FW507-4G11

Annotation: Holliday junction DNA helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 145 PF03652: RuvX" amino acids 18 to 142 (125 residues), 114.2 bits, see alignment E=2.9e-37 TIGR00250: putative transcription antitermination factor YqgF" amino acids 20 to 141 (122 residues), 85.2 bits, see alignment E=2e-28

Best Hits

Swiss-Prot: 82% identical to YQGF_CUPNH: Putative pre-16S rRNA nuclease (H16_A2915) from Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)

KEGG orthology group: K07447, putative holliday junction resolvase [EC: 3.1.-.-] (inferred from 82% identity to reh:H16_A2915)

Predicted SEED Role

"Putative Holliday junction resolvase YggF"

Isozymes

Compare fitness of predicted isozymes for: 3.1.-.-

Use Curated BLAST to search for 3.1.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YIT6 at UniProt or InterPro

Protein Sequence (145 amino acids)

>RR42_RS15870 Holliday junction DNA helicase (Cupriavidus basilensis FW507-4G11)
MPEDGATPAPRQLPSDGTVLAFDYGEKKIGVALGNFVTREAHALVIIPNITVEGRFEAVT
ALIDEWAPVQLVVGMPTNPDGSQQPSMRLARRFGNQLNGRFGLPVAWVDESYTSIAAEMA
GARKGALDAEAASLILQQYFDQHPL