Protein Info for RR42_RS15085 in Cupriavidus basilensis FW507-4G11
Annotation: LacI family transcriptional regulator
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 41% identical to YTCB_PSESQ: UPF0065 protein in tcbD-tcbE intergenic region from Pseudomonas sp. (strain P51)
KEGG orthology group: None (inferred from 65% identity to cti:RALTA_B0330)Predicted SEED Role
"Tricarboxylate transport protein TctC"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A0C4YBY2 at UniProt or InterPro
Protein Sequence (325 amino acids)
>RR42_RS15085 LacI family transcriptional regulator (Cupriavidus basilensis FW507-4G11) MRFPIRLCATALCWLAAGTSSLAHAQAWPAAKPIRLVVTYAPGGGADTMARMISPRLGQE LGQTIVVDNRPGAGGQIGTDLVAKSAPDGYTVLLDAASFAANPSLYKRLPYDPVKSFIPV SVLALYPNMLVVNPRFPAKTTQELVAMARAKPGSIAYASSGNGSAQHLAGALFAQRMKLD LLHVPYKGGGPAMADVIAGQVPVFFANTASGLQHVRAGKLRVLGVTGARRTAILPDTPTL AEAGVPHYEVYEWNGVFLPAGTPPEIVKRLSDAIRKVINLPENRERVTSLGGEIVAGTPA EAAKFVQAQTTEWAKVIKEGNIQLD