Protein Info for RR42_RS14810 in Cupriavidus basilensis FW507-4G11

Annotation: DEAD/DEAH box helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 496 PF00270: DEAD" amino acids 37 to 210 (174 residues), 168.1 bits, see alignment E=2.2e-53 PF04851: ResIII" amino acids 39 to 205 (167 residues), 33.6 bits, see alignment E=5.5e-12 PF00271: Helicase_C" amino acids 252 to 358 (107 residues), 105.6 bits, see alignment E=2.6e-34

Best Hits

KEGG orthology group: None (inferred from 85% identity to reu:Reut_A0899)

Predicted SEED Role

"ATP-dependent RNA helicase Bcep18194_A5658" in subsystem ATP-dependent RNA helicases, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YI19 at UniProt or InterPro

Protein Sequence (496 amino acids)

>RR42_RS14810 DEAD/DEAH box helicase (Cupriavidus basilensis FW507-4G11)
MTTTTTDQTTPEITFDSFGLDARIQRALSEQGYTKPTPIQEQAIPVVLLGKDVMGAAQTG
TGKTAGFALPIIQRLLPLASASASPARHPVRALMLTPTRELADQVYDNVARYARFTDLRS
TVVFGGVDMNPQTEALRRGVEILVATPGRLLDHVQQKSVNLSQVQMLVLDEADRMLDMGF
LPDLQRIINLLPAQRQTLLFSATFSSEIKRLAASYLRQPVTIEVARSNSANENVRQTVFQ
VEDGHKQAAVVHLLKKRAAEGLSRQCIVFVNSKIGCSRLARHLEREGINAAAIHGDKTQT
ERMQTLDGFKQGNIDALVATDVAARGLDIPDMPCVINFDLPFSAEDYVHRIGRTGRAGAS
GDALSIYVPADERLLVDIEKLLKRSLPRTPLDGFDPTGAGARADENDRRRARTEVRRPRA
NGDGDEPRARRNDPASSRNAFRASDDSFFSRPYEPSAAAIAAQPDVTDNGAAAFGRGRPA
PKRQLAALLGGVPRKS