Protein Info for RR42_RS14420 in Cupriavidus basilensis FW507-4G11

Annotation: branched-chain amino acid transporter permease subunit LivH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 transmembrane" amino acids 18 to 39 (22 residues), see Phobius details amino acids 46 to 65 (20 residues), see Phobius details amino acids 71 to 91 (21 residues), see Phobius details amino acids 103 to 122 (20 residues), see Phobius details amino acids 155 to 175 (21 residues), see Phobius details amino acids 204 to 227 (24 residues), see Phobius details amino acids 234 to 270 (37 residues), see Phobius details amino acids 281 to 300 (20 residues), see Phobius details PF02653: BPD_transp_2" amino acids 12 to 292 (281 residues), 165.5 bits, see alignment E=7.1e-53

Best Hits

Swiss-Prot: 62% identical to BRAD_PSEAE: High-affinity branched-chain amino acid transport system permease protein BraD (braD) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K01997, branched-chain amino acid transport system permease protein (inferred from 96% identity to cti:RALTA_A2124)

MetaCyc: 58% identical to branched chain amino acid/phenylalanine ABC transporter membrane subunit LivH (Escherichia coli K-12 substr. MG1655)
ABC-15-RXN [EC: 7.4.2.2]; 7.4.2.2 [EC: 7.4.2.2]; 7.4.2.2 [EC: 7.4.2.2]; 7.4.2.2 [EC: 7.4.2.2]

Predicted SEED Role

"High-affinity branched-chain amino acid transport system permease protein LivH (TC 3.A.1.4.1)" in subsystem ABC transporter branched-chain amino acid (TC 3.A.1.4.1) (TC 3.A.1.4.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YBR0 at UniProt or InterPro

Protein Sequence (308 amino acids)

>RR42_RS14420 branched-chain amino acid transporter permease subunit LivH (Cupriavidus basilensis FW507-4G11)
MNEFLPQFTQQLVNGLTLGAIYALIAIGYTMVYGIIGMINFAHGEIYMIGAYVGLVTLTA
IGASAGYPLPLVLGAALLVSVLVTGLYGFAVERVAYRPLRGGPRLVPLISAIGMSIFLQN
YVQIGQGARDMSVPVLISGAIEFQMGSDFTVTVPYSRLLIVGVTLVLMLALTLFIGHSRM
GRACRACAEDMRMANLLGIDTNRVISFTFVLGAMLAAVGGVLIGLTIGKLNPYIGFVAGI
KAFTAAVLGGIGSIPGAMLGGVLLGLAETFASGYMPAEYKDVVAFGLLVLILLFRPTGLL
GKPDVEKV