Protein Info for RR42_RS14250 in Cupriavidus basilensis FW507-4G11

Annotation: epimerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 370 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF01370: Epimerase" amino acids 4 to 248 (245 residues), 53.1 bits, see alignment E=3.1e-18 PF07993: NAD_binding_4" amino acids 5 to 239 (235 residues), 82.4 bits, see alignment E=3.1e-27

Best Hits

KEGG orthology group: None (inferred from 56% identity to bte:BTH_II1737)

Predicted SEED Role

"Nucleoside-diphosphate-sugar epimerases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YHT4 at UniProt or InterPro

Protein Sequence (370 amino acids)

>RR42_RS14250 epimerase (Cupriavidus basilensis FW507-4G11)
DSLLLTGATGFIGGNVMVAAINAGLARRLLCLVRGVDAADALARLRENAIQCGLLRSRVD
WLTEDNILLGVLDSDFSPAAQARIAGVTHVINCAAMASFSADAQVTRINVQDTLRFASRF
AGSATLQRFIHVGTAMACGTQRGPRIAERDAGHGGASDLSHLVPYTRSKQEVEVLLRNSF
PDLPLVVARPSIVVGHTVLGTQPSASIFWLFRIIHQSRRYTAGPHTRIDVIAVDDCARAL
LRLAVKPELAFDAYHLSAGARAPTIAQVIAAMDEAVSIDGEPAYRRCPASELPALASDVA
RKERNSNRRLIERALRLYSGFAELGYVFDNGRIREEIDFEPLSITDYVSECMRTSRGVGI
LEQMSWDFKS