Protein Info for RR42_RS14030 in Cupriavidus basilensis FW507-4G11

Annotation: DNA recombination protein RecO

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 292 PF11967: RecO_N" amino acids 60 to 132 (73 residues), 75.6 bits, see alignment E=2.5e-25 TIGR00613: DNA repair protein RecO" amino acids 61 to 234 (174 residues), 109 bits, see alignment E=1.3e-35 PF02565: RecO_C" amino acids 140 to 283 (144 residues), 63.8 bits, see alignment E=1.6e-21

Best Hits

Swiss-Prot: 84% identical to RECO_CUPNJ: DNA repair protein RecO (recO) from Cupriavidus necator (strain JMP 134 / LMG 1197)

KEGG orthology group: K03584, DNA repair protein RecO (recombination protein O) (inferred from 84% identity to reu:Reut_A2250)

Predicted SEED Role

"DNA recombination and repair protein RecO" in subsystem DNA repair, bacterial RecFOR pathway

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YHQ9 at UniProt or InterPro

Protein Sequence (292 amino acids)

>RR42_RS14030 DNA recombination protein RecO (Cupriavidus basilensis FW507-4G11)
MSDRAGGPALKARRIDPVVEEAAELLGSHAVPGMAVAEQRAMMDRALRIVPARTELRVAN
QPGFVLHAWPYRETSLILDVFTRDHGRVAMVAKGAKRPHSALRPVLQHFQPISLSWSGRG
EVKTLTRAEWVGGMLPLASDALLSGFYLNELLLRFCAREDAHVTLFRQYMATLTQLSHGE
PAGLVLRGFERVLLQETGFAVAFDECANSGETVEPELDYVYQPERGVRRAQASDPSSWPV
VSGRTLLDMSQDDYSRTQTVTQSRALMRFLLHYYLQGAPLKTRQILIDLHYL