Protein Info for RR42_RS13450 in Cupriavidus basilensis FW507-4G11

Annotation: PhoU family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 234 TIGR02135: phosphate transport system regulatory protein PhoU" amino acids 8 to 220 (213 residues), 237 bits, see alignment E=8.7e-75 PF01895: PhoU" amino acids 21 to 109 (89 residues), 80.6 bits, see alignment E=4.7e-27 amino acids 130 to 210 (81 residues), 67.8 bits, see alignment E=4.6e-23

Best Hits

Swiss-Prot: 58% identical to PHOU_BURSP: Phosphate-specific transport system accessory protein PhoU homolog (phoU) from Burkholderia sp.

KEGG orthology group: K02039, phosphate transport system protein (inferred from 91% identity to reh:H16_A2440)

Predicted SEED Role

"Phosphate transport system regulatory protein PhoU" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YB57 at UniProt or InterPro

Protein Sequence (234 amino acids)

>RR42_RS13450 PhoU family transcriptional regulator (Cupriavidus basilensis FW507-4G11)
MSDKHLSTQFDADLNAISTKLLQMGGLVESQIENAMRALSEFDAGLADQVIAREHHLNAL
ELEIDADCGNIIARRQPTARDLRLVMAISKTITNLERAGDEAEKIAKRTKHIMEDAGAHQ
INYSEVKFSGDLAIALLRQALDAFARLDTVAAARIVKDDKAIDDEFRAFVRKLITYMMED
PRTISVALDFLFIAKAIERIGDHAKNIAEFIIYIVKGTDVRHASREDMEREALS