Protein Info for RR42_RS12965 in Cupriavidus basilensis FW507-4G11
Annotation: glycerol-3-phosphate transporter permease
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 65% identical to UGPA_RHIME: sn-glycerol-3-phosphate transport system permease protein UgpA (ugpA) from Rhizobium meliloti (strain 1021)
KEGG orthology group: K05814, sn-glycerol 3-phosphate transport system permease protein (inferred from 89% identity to reu:Reut_A2051)MetaCyc: 63% identical to sn-glycerol 3-phosphate ABC transporter membrane subunit UgpA (Escherichia coli K-12 substr. MG1655)
ABC-34-RXN [EC: 7.6.2.10]; 7.6.2.10 [EC: 7.6.2.10]
Predicted SEED Role
"Glycerol-3-phosphate ABC transporter, permease protein UgpA (TC 3.A.1.1.3)" in subsystem Glycerol and Glycerol-3-phosphate Uptake and Utilization (TC 3.A.1.1.3)
Isozymes
No predicted isozymesUse Curated BLAST to search for 7.6.2.10
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A0C4Y403 at UniProt or InterPro
Protein Sequence (293 amino acids)
>RR42_RS12965 glycerol-3-phosphate transporter permease (Cupriavidus basilensis FW507-4G11) MEKRVVFRSSWLPYLLVLPQMAVTLIFFFWPAGQALYQSVLRQDAFGIDLQFVGLENFRD LFSDAQYLNAFRVTGVFAVGVTLVGLTVSLMLAYFADRVVRGASGYKMLLIWPYAVAPAV AGVLWMFMFNPTLGVVSYALHRFGVDWNFLLNSNQAMLLVVLIAAWKQISYNFLFFLAGL QSIPKSLIEAAAIDGAGPWRRFWSIIFPLLSPTTFFLMVINVVYAFFDTFAIIDAVTHGG PVNATNTLVYKVYQDGFRGLDIGGSAAQSVVLMGIVIVLTVVQFRYVERKVQY