Protein Info for RR42_RS11325 in Cupriavidus basilensis FW507-4G11

Annotation: acyl-homoserine lactone acylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 820 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF01804: Penicil_amidase" amino acids 49 to 798 (750 residues), 805.8 bits, see alignment E=2.6e-246

Best Hits

KEGG orthology group: K01434, penicillin amidase [EC: 3.5.1.11] (inferred from 78% identity to reu:Reut_A1841)

Predicted SEED Role

"Penicillin amidase (EC 3.5.1.11)" (EC 3.5.1.11)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.11

Use Curated BLAST to search for 3.5.1.11

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YG94 at UniProt or InterPro

Protein Sequence (820 amino acids)

>RR42_RS11325 acyl-homoserine lactone acylase (Cupriavidus basilensis FW507-4G11)
MRWLKRLTWLVLTLAVLLLVCAFGAYVWYRQASQPQTAGTLKLPGLRESVSIVRDRHAVP
HIKAANAQDAYFALGFVHAQDRLWQLQMNKRIASGRLAEILGPSALDTDRFLRTLGVRRN
AEAILAQSSAETRAMLQAYADGVNACIDGRKGPLPPEFLILRTRPEHWEPADTLAWQTMM
AWDLGGNWTQETLRMRLAQVLPVSRINELLAPYPGERPLRTMDYGNLYRHLAPLATAMAR
VEQQAPAGYVEGMGSNNWVVSGAHTRSGKPLLANDPHLGLQAPALWYFAQMQAPGLDVTG
ATLPGMPAVVLGHNQRIAWGFTNTAPDVQDLYIERLQPGSTQRYQTPDGWAEFVTRTETI
HVKGAPDVTLNVRETRHGPVISDAAEPVATAAAPLGAQYVVAFQWTALRADDRTVQAGLA
LNRATDWASFLAALRDFHSPQQNIVYADVDGNIGFIAPGRVPLRRADNDLKGLAPAPGWD
ARYDWSGFIPFEQLPRSFNPPEGVIATANQKIVEDDYPYFLTSEWTVPYRYQRIRTLIDA
TERHTLDSFGAIQKDTLSLAVRDALPLLLASPIASDPALPERERALIASLRKWDGDMQPG
LSEPLVATAWLRELSRVLFEDKVGDTLFNRLWEQRNVQQPMLNVLRNPRGQGTFWCDDST
TPATESCDDAVAKAWRLAIADLDRRYGDKPERWRWGQAHAARSEHKPFGKQPYLSGLFNV
KVPSGGDTYTVNVGRHNLRDEAAPFESVHAASLRAIYDLSDLAESRFMDSTGQSGNVTST
HYRDWTDKWAAVQYITMAPGRRAPGNEAFDTLVLQPAGRR