Protein Info for RR42_RS06515 in Cupriavidus basilensis FW507-4G11

Annotation: electron transfer flavoprotein-ubiquinone oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 561 PF13450: NAD_binding_8" amino acids 22 to 66 (45 residues), 26.2 bits, see alignment 2.3e-09 PF21162: ETFQO_UQ-bd" amino acids 221 to 314 (94 residues), 153.2 bits, see alignment E=7.1e-49 PF05187: ETF_QO" amino acids 457 to 558 (102 residues), 175.7 bits, see alignment E=6.6e-56

Best Hits

KEGG orthology group: K00311, electron-transferring-flavoprotein dehydrogenase [EC: 1.5.5.1] (inferred from 94% identity to rme:Rmet_1146)

Predicted SEED Role

"Electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1)" in subsystem Acetyl-CoA fermentation to Butyrate or Anaerobic respiratory reductases (EC 1.5.5.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.5.5.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y6V3 at UniProt or InterPro

Protein Sequence (561 amino acids)

>RR42_RS06515 electron transfer flavoprotein-ubiquinone oxidoreductase (Cupriavidus basilensis FW507-4G11)
MNQQQLLEQYGPREAMEYDVVIVGGGPAGLATAIRLKQLAQEKGTEVNVCVLEKGSEPGA
HILSGAIMDPVALNELIPNWKELGAPLNQPVAEDKFLFLNETGSKATPSALLPECFHNHG
NYIVSLSNFTRWLGQQAEGLGVEIFPGFPAAEVLYNDDGSVKGVATGNMGINKEGEPTEN
FQLGMELHAKYTIFAEGSRGHLGKQLIARYKLDDGKDPQSYGIGLKELWEIDPAKHQPGL
VVHTAGWPLDPATYGGSFLYHMEDNKVAVGFVVGLDYTNPWLSPFEEFQRFKTHPEIRTY
FEGGKRISYGARAITAGGLLSLPKTVFPGGALVGCDAGYLNASRIKGSHAAIKTGMMAAE
AAYDALQANRQHDELTAYPTAFENSWLHKELLQAKNFKQWFKKGRTTATLMTGIEQWLLP
KLGIRNPPWTLHREKPDHVYLKPAAECQQIVYPKPDGKLTFDRLSSVFISNTNHEENQPA
HLTLKDASVPVNVNWDKFAGPESRYCPAGVYEFVQNDDGKERLQINAQNCVHCKTCDIKD
PTQNIVWVTPEGGGGPNYVGM