Protein Info for RR42_RS06450 in Cupriavidus basilensis FW507-4G11

Annotation: membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 457 transmembrane" amino acids 37 to 64 (28 residues), see Phobius details amino acids 103 to 123 (21 residues), see Phobius details amino acids 144 to 168 (25 residues), see Phobius details amino acids 180 to 203 (24 residues), see Phobius details amino acids 215 to 236 (22 residues), see Phobius details amino acids 252 to 277 (26 residues), see Phobius details amino acids 290 to 306 (17 residues), see Phobius details TIGR00765: YihY family inner membrane protein" amino acids 27 to 277 (251 residues), 222.3 bits, see alignment E=4.8e-70 PF03631: Virul_fac_BrkB" amino acids 32 to 277 (246 residues), 194.1 bits, see alignment E=1.7e-61

Best Hits

Swiss-Prot: 72% identical to Y1559_RALSO: UPF0761 membrane protein RSc1559 (RSc1559) from Ralstonia solanacearum (strain GMI1000)

KEGG orthology group: K07058, membrane protein (inferred from 84% identity to cti:RALTA_A1222)

Predicted SEED Role

"Ribonuclease BN (EC 3.1.-.-)" in subsystem LMPTP YfkJ cluster or tRNA processing (EC 3.1.-.-)

Isozymes

Compare fitness of predicted isozymes for: 3.1.-.-

Use Curated BLAST to search for 3.1.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y166 at UniProt or InterPro

Protein Sequence (457 amino acids)

>RR42_RS06450 membrane protein (Cupriavidus basilensis FW507-4G11)
MLAARIVRLRREWNLQKLRALTRYALRRAGEGRLPQVAASLTFTTVLAVVPVLTVAFALL
AAFPVFREFRSATESFLFQNLIPGNVSNSITSYLGQFAKNAKGLTAVGLGGLMVTSVLTM
LTVEDALNAIWRVKQRRPLAQRVLVFWAVLTLGPVLIGASLSISSYLISVSAGYVGTMPF
GLGLVVGLTPVLLSAVAFAFLYTAVPNANVEWRDAIAAGLVAALAFELAKRGFGYFVTHI
PTYTAVYGTFAALPIFLLWIYLSWLVTLLGATIAANLPVIRQGYWRRRTFAGSEFFDALG
VLYLLYRARDEVPRSVGELDLGRKLRVEADYLAGLLGKLKGMHLVGRLAQDRGQAHWALL
CDPGQVTLRTLHDRLVLNLPRLPRTALAQQLRGADALKQVLDNPRLDQPLEAVFRRQQQD
QQDQQAQTQTGTAAQERPADSARRTLEVVPPGWHGQV