Protein Info for RR42_RS05500 in Cupriavidus basilensis FW507-4G11

Annotation: preprotein translocase subunit SecG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 122 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details transmembrane" amino acids 54 to 76 (23 residues), see Phobius details TIGR00810: preprotein translocase, SecG subunit" amino acids 6 to 76 (71 residues), 86.3 bits, see alignment E=5.6e-29 PF03840: SecG" amino acids 7 to 76 (70 residues), 72.9 bits, see alignment E=9.8e-25

Best Hits

Swiss-Prot: 41% identical to SECG_HAEIN: Protein-export membrane protein SecG (secG) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K03075, preprotein translocase subunit SecG (inferred from 89% identity to reh:H16_A1048)

Predicted SEED Role

"Preprotein translocase subunit SecG (TC 3.A.5.1.1)" in subsystem Murein hydrolase regulation and cell death (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y8L4 at UniProt or InterPro

Protein Sequence (122 amino acids)

>RR42_RS05500 preprotein translocase subunit SecG (Cupriavidus basilensis FW507-4G11)
MAIFKTLLVVAQILSALGVIGLVLLQHGKGADVGAAFGSGASGSLFGATGSANFLSRTTA
VLATLFFICTLSLTLMGNYRPAASLGVMGSAPAVAPAVAGASAPAAASAAAASNPSAPAV
PK