Protein Info for RR42_RS04975 in Cupriavidus basilensis FW507-4G11

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 491 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 327 to 478 (152 residues), 105.3 bits, see alignment E=1.4e-34 PF00990: GGDEF" amino acids 331 to 478 (148 residues), 112.5 bits, see alignment E=1.8e-36

Best Hits

KEGG orthology group: None (inferred from 86% identity to reu:Reut_A2462)

Predicted SEED Role

"GGDEF family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YCN0 at UniProt or InterPro

Protein Sequence (491 amino acids)

>RR42_RS04975 histidine kinase (Cupriavidus basilensis FW507-4G11)
MATTETSRIDNEYKALFQLAPVSLWLEDFSAVREHFQALRAQGVTDLRGHLRANPEEVAH
CSARIRVLDVNQRTLDLFRAADLTDLVNNLDTVFRDDMFDQHVEELGQLWDGGLRFSSQT
VNYTLEGKRLDIRLDATVMPGHEATWERVLLSIEDITARVATERELRRSEQYALGLFEHS
PVSLWVEDFSAVKVLLDEVRGAGISDFRTFLNVHPDFISRCMQEIRVLDVNQQTLLMFSA
STKEELLSRLGDVFRDNMRIQFAEQLIDLWNEKLWQQREVINYALDGRAVDVFMQWSVFP
GREAEWDQVLVSLTDITARKKAEAYVEFLGKHDVLTKLYNRAYYEDELARLGRKGPWPVS
VIAVDLNGLKQVNDQLGHGDGDALLRRTGEALKKAVGDQACVARVGGDEFMVLLPARDER
GAATVVEQIHQVVELNNQFYPGTALSLSIGTASCGATDRLSDAVKLADARMYQAKRAHYE
ALDDERERRRR