Protein Info for RR42_RS04705 in Cupriavidus basilensis FW507-4G11

Annotation: septum formation inhibitor Maf

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 201 PF02545: Maf" amino acids 6 to 196 (191 residues), 194.1 bits, see alignment E=9.1e-62 TIGR00172: septum formation protein Maf" amino acids 6 to 195 (190 residues), 158.5 bits, see alignment E=6.5e-51

Best Hits

Swiss-Prot: 86% identical to NTPPA_CUPNJ: dTTP/UTP pyrophosphatase (Reut_A2528) from Cupriavidus necator (strain JMP 134 / LMG 1197)

KEGG orthology group: K06287, septum formation protein (inferred from 86% identity to reu:Reut_A2528)

Predicted SEED Role

"Septum formation protein Maf" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y839 at UniProt or InterPro

Protein Sequence (201 amino acids)

>RR42_RS04705 septum formation inhibitor Maf (Cupriavidus basilensis FW507-4G11)
MTHTFLYLASQSPRRRELLTQLGVAYELLLADDNEDAEALEVVLPGESPDDYVQRVCALK
AEAALRRRERRALPDAPILTSDTTVCLDGEILGKPADDADAARMLAALSGRTHRVLTAVT
VVSALGQRHALSVSEVSFRTMTADEIAAYVASGEPAGKAGAYGIQGRAAEFVERIDGSYS
GIMGLPLFETASLLRQAHLRF