Protein Info for RR42_RS04195 in Cupriavidus basilensis FW507-4G11
Annotation: membrane protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 70% identity to reh:H16_A2983)Predicted SEED Role
"Thymidylate kinase (EC 2.7.4.9)" (EC 2.7.4.9)
MetaCyc Pathways
- superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (18/18 steps found)
- pyrimidine deoxyribonucleotides de novo biosynthesis I (9/9 steps found)
- superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) (12/14 steps found)
- pyrimidine deoxyribonucleotides de novo biosynthesis III (8/9 steps found)
- pyrimidine deoxyribonucleotide phosphorylation (4/4 steps found)
- pyrimidine deoxyribonucleotides de novo biosynthesis IV (6/7 steps found)
- pyrimidine deoxyribonucleotides biosynthesis from CTP (6/8 steps found)
- pyrimidine deoxyribonucleotides de novo biosynthesis II (5/7 steps found)
- superpathway of pyrimidine deoxyribonucleoside salvage (5/9 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.7.4.9
Use Curated BLAST to search for 2.7.4.9
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A0C4Y5K9 at UniProt or InterPro
Protein Sequence (365 amino acids)
>RR42_RS04195 membrane protein (Cupriavidus basilensis FW507-4G11) MQLDNNAFHAAAYEQPAATVRPLRFEFIGSGSEFFRIWIVNTLLTIVTLGIYSAWAKVRT MQYFYRNTRLDGASFDYHGRASAILKGRAIVFGLAMVFQLASHISLFVALALGLALAVVF PLLLVRSLRFRMANSSYRGLRFAFTGSDAQAYKVFLLWPVLTALSLYALAPLAHQRFKQY QHDNTRFGTAPFGISASAGGFYGVYLRAFGMMVAVVVGMSVAGGMLGRGIGAGIGAGMGA GMGAPAVAGIMAVIGFFVAMMAVGPFFMARLQNLVWNHTTLAPHAFRSEVKAGRLLFIFA TNMIANALTLGLFLPFARVRSMRYRIESMTMLAAGPLDAFVAGETQHVGALGDAAVDWYD IDIAL