Protein Info for RR42_RS03945 in Cupriavidus basilensis FW507-4G11

Annotation: chloride channel protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 579 transmembrane" amino acids 14 to 40 (27 residues), see Phobius details amino acids 62 to 82 (21 residues), see Phobius details amino acids 113 to 130 (18 residues), see Phobius details amino acids 136 to 153 (18 residues), see Phobius details amino acids 161 to 185 (25 residues), see Phobius details amino acids 196 to 215 (20 residues), see Phobius details amino acids 230 to 255 (26 residues), see Phobius details amino acids 267 to 285 (19 residues), see Phobius details amino acids 305 to 326 (22 residues), see Phobius details amino acids 332 to 352 (21 residues), see Phobius details amino acids 359 to 386 (28 residues), see Phobius details amino acids 392 to 411 (20 residues), see Phobius details PF00654: Voltage_CLC" amino acids 74 to 406 (333 residues), 263.9 bits, see alignment E=2.3e-82 PF00571: CBS" amino acids 441 to 490 (50 residues), 16.9 bits, see alignment 6.5e-07 amino acids 515 to 558 (44 residues), 30.4 bits, see alignment 4.2e-11

Best Hits

KEGG orthology group: None (inferred from 82% identity to reu:Reut_A2674)

Predicted SEED Role

"Chloride channel protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y7U4 at UniProt or InterPro

Protein Sequence (579 amino acids)

>RR42_RS03945 chloride channel protein (Cupriavidus basilensis FW507-4G11)
MHFEKRDYAVDRRLLLLAALAPLIGAISTAAAVLLLNLIRFFTNLFFYQTLSLADRSPAQ
HALGAWVIVVPAVGGLLVGLMARYGSDKIRGHGIPEAIEAVLFGKSKMSPRVAVLKPLSS
GIVIGSGGPFGAEGPIIMTGGSIASLLAQYLHLTAAERKTLLVAGACAGMTAIFGTPVAA
VLLAVELLLFELRPRSLLPVALACAVAGFLRTMVFEPGPLFALHTAPASTMALGSCVVAG
LLCGVLGAALTLALYRTEDQFSKLKLHWMWWPAIGGLVVGIGGYFEPRALGVGYDVIADL
LHNRMAIGVVLALLTVKAIIWVAALGSGTSGGVLAPLLMLGAGLGVALAPWLPGASAPLW
ALVCMAGVLGSVLGAPLTAIVFAFGLTHDSNALLPLLLTVAMAHGFTVLTMKRSIMTEKI
ARRGLHIYREYGVDPLERQHVADLMTTAVVSVDGEQPVHVLWASHFGEHAPHRGYPVVCA
ARVVGMLERNALRGREASMEAGRALMAPLQPHQVLLPAQTARVAAGRMAELGVSRLPVVA
DLDSMRLVGVVSLRDLLRPSGQVLHEETRRERLRGTAAA