Protein Info for RR42_RS03245 in Cupriavidus basilensis FW507-4G11

Annotation: D-alanyl-D-alanine carboxypeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 510 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details PF02113: Peptidase_S13" amino acids 60 to 505 (446 residues), 269.3 bits, see alignment E=6.1e-84 TIGR00666: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase" amino acids 88 to 487 (400 residues), 188.5 bits, see alignment E=8.5e-60

Best Hits

KEGG orthology group: K07259, D-alanyl-D-alanine carboxypeptidase / D-alanyl-D-alanine-endopeptidase (penicillin-binding protein 4) [EC: 3.4.16.4 3.4.21.-] (inferred from 79% identity to reu:Reut_A0564)

Predicted SEED Role

"D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4)" in subsystem Peptidoglycan Biosynthesis (EC 3.4.16.4)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.16.4, 3.4.21.-

Use Curated BLAST to search for 3.4.16.4 or 3.4.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y5D1 at UniProt or InterPro

Protein Sequence (510 amino acids)

>RR42_RS03245 D-alanyl-D-alanine carboxypeptidase (Cupriavidus basilensis FW507-4G11)
MGIMPNRPSPILHRLLPLCAAGLLCISGVSTAAKTPVHKTKATHAASASAEPRSGLPGSV
TAALKRAHVPASATSFYVIKVGAPAPRASWNAQTPMNPASTMKLVTTFAGLQLLGPGYRW
QTALYADNQPAADGTVNGNVYLRGYGDPKLVPEEMAKLVNSARTAGATTINGDVVLDRSY
FDSALDKGATIDGETQRAYNVSPDALLYAFKTLSFTITPDPANQSVAVSVTPALAQLKLD
NRLALSHGKCGDWSARARPAVTPQADGTVLASFDGSYAADCGEHVVNIATLSHNEFTWGG
FVAEWQLAGGRFTHQPALRMGRAPRNAFLLARHYGQPLSEIVRDINKFSNNVMARQLYLT
IGAEMDRSGPASTTRSAKVVQRWLARQGLDMPGLALDNGSGLSREERISAYDMSRLLQQA
LASEVGPVLIDSLPILGVDGTLRNRLTHAGAAGNAYMKTGTLNDVRALAGYVDALNGDRY
VVVSYINHANAAQAREAHDALLQWVYQGAP