Protein Info for RR42_RS03235 in Cupriavidus basilensis FW507-4G11

Annotation: translation factor Sua5

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 328 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family" amino acids 5 to 208 (204 residues), 173.1 bits, see alignment E=2.1e-55 PF01300: Sua5_yciO_yrdC" amino acids 16 to 196 (181 residues), 182.6 bits, see alignment E=5.1e-58 PF03481: Sua5_C" amino acids 199 to 324 (126 residues), 74.7 bits, see alignment E=1.1e-24

Best Hits

KEGG orthology group: K07566, putative translation factor (inferred from 85% identity to reu:Reut_A0553)

Predicted SEED Role

"TsaC protein (YrdC domain) required for threonylcarbamoyladenosine t(6)A37 modification in tRNA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y557 at UniProt or InterPro

Protein Sequence (328 amino acids)

>RR42_RS03235 translation factor Sua5 (Cupriavidus basilensis FW507-4G11)
MSRMPTSAELDQAVQLLEAGELVAFPTETVYGLGADAENPEAIARIYAAKGRPPNHPIIV
HVVDGGDISYWVDDVPPAAQDLIDAFWPGPLTLILKRAEHIPAAVAGGQDSIGLRCPSHP
VAQALLSRFKRGRGGIAAPSANKFGQVSPTTAQHVRDEFGDAVFVLEGDGVEVGIESTIV
DLSRLEQGIGPVLLRPGAITPAMMAQVLGVTPLPPDAAAPRASGTLKAHYAPHTPLALCS
AADLPAQLADLPADARVAWVGVQAAADPRCVWVQAPADAEGYARALYRLLRRLDGDGFAR
LVFEALPAGHEWDAVRDRLQRAAAAFGG