Protein Info for RR42_RS02725 in Cupriavidus basilensis FW507-4G11

Annotation: Fis family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 77 PF02954: HTH_8" amino acids 34 to 73 (40 residues), 48.7 bits, see alignment E=2.6e-17

Best Hits

Swiss-Prot: 78% identical to FISL_RALSO: Putative Fis-like DNA-binding protein (RSc0505) from Ralstonia solanacearum (strain GMI1000)

KEGG orthology group: K03557, Fis family transcriptional regulator, factor for inversion stimulation protein (inferred from 95% identity to rme:Rmet_0428)

Predicted SEED Role

"DNA-binding protein Fis" in subsystem DNA structural proteins, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y530 at UniProt or InterPro

Protein Sequence (77 amino acids)

>RR42_RS02725 Fis family transcriptional regulator (Cupriavidus basilensis FW507-4G11)
MSRNAIDQCIRDSLGAYFRDLDGEEPSNMYNMVLEAVERPLLEAVMARAERNQSLAAAYL
GINRNTLRKKLQQHGLL