Protein Info for RR42_RS02535 in Cupriavidus basilensis FW507-4G11

Annotation: metal ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 631 transmembrane" amino acids 44 to 66 (23 residues), see Phobius details amino acids 78 to 100 (23 residues), see Phobius details amino acids 162 to 185 (24 residues), see Phobius details amino acids 191 to 211 (21 residues), see Phobius details amino acids 275 to 295 (21 residues), see Phobius details amino acids 309 to 330 (22 residues), see Phobius details PF00664: ABC_membrane" amino acids 46 to 320 (275 residues), 149.9 bits, see alignment E=1.9e-47 PF00005: ABC_tran" amino acids 385 to 534 (150 residues), 113.3 bits, see alignment E=2.1e-36

Best Hits

Swiss-Prot: 46% identical to ATM1_YARLI: Iron-sulfur clusters transporter ATM1, mitochondrial (ATM1) from Yarrowia lipolytica (strain CLIB 122 / E 150)

KEGG orthology group: K06147, ATP-binding cassette, subfamily B, bacterial (inferred from 88% identity to reu:Reut_A0452)

Predicted SEED Role

"Lipid A export ATP-binding/permease protein MsbA" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y4R2 at UniProt or InterPro

Protein Sequence (631 amino acids)

>RR42_RS02535 metal ABC transporter permease (Cupriavidus basilensis FW507-4G11)
MRRYSTSAEPSPAQPSSLFGKSNVPRSDWQTVRNLLPYVWHYKWRVILALVCLVAAKVAN
LGVPVLMKKLVDNMNVPAGSASALLVVPVGLIVAYGILRLSGTLFTELREILFSKVTQSA
VREIALQVFRHLHALSLRFHLDRQTGGMSRDIERGTRGIQSLISYSLYSILPTLVEMGLV
MGFFILHYDIWFAAITGCALVSYIVFTIVVTEWRTHFRRRMNELDSRANQKAIDSLLNFE
TVKYFGNEEYEAGRYDENLRKYRTAAIRSQNSLSFLNFGQQAIIATGLILILWRATVGVA
AGKLTLGDLVLVNTLMIQLYIPLNFLGVIYREIKQATTDMDRMFVLLGTNREVADAPDAA
ALRVQGAAVRFNHVGFGYESNRVILDEVDFAIAAGTTTAVVGHSGSGKSTLARLLFRFYD
VSSGGIEIDGQDIRSITQDSLRRAIGIVPQDTVLFNDSIYYNIAYGRPDASRDEVIEAAR
AAQIDGFIRDLPQGYDTPVGERGLKLSGGEKQRVAIARTLLKNPPILVFDEATSALDSRT
EQAIQAELMRLAQNRTTLLIAHRLSTVVHADQILVMDHGRIIERGTHAELMRLDGRYAEM
WRIQARSAAQSEAPVEDAALAIEAGDATQDA