Protein Info for RR42_RS02420 in Cupriavidus basilensis FW507-4G11

Annotation: SAM-dependent methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 211 PF05724: TPMT" amino acids 24 to 206 (183 residues), 126.4 bits, see alignment E=2e-40 PF08241: Methyltransf_11" amino acids 63 to 154 (92 residues), 32.4 bits, see alignment E=1.8e-11 PF13649: Methyltransf_25" amino acids 64 to 151 (88 residues), 34.6 bits, see alignment E=3.9e-12

Best Hits

KEGG orthology group: None (inferred from 72% identity to reu:Reut_A0435)

Predicted SEED Role

"SAM-dependent methyltransferases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y4P2 at UniProt or InterPro

Protein Sequence (211 amino acids)

>RR42_RS02420 SAM-dependent methyltransferase (Cupriavidus basilensis FW507-4G11)
MTKSDNAPNQAAAPPAFATRNAGDPAFWDERFEKGFMPWDLGGVPADFEAFASAMAPCPT
LIPGCGNGWEAGWLHARGWPVTAIDFSPEAVASARRSLGPAGAVVHEADFFAFAPEPACQ
WIYERAFLCALPPAMRAGYAARVAQLLPPGGLLAGYFFLDETRGGPPFAIPEAELRALLE
PAFELVQARAATGSLPVFAGREQWQVWRRRA