Protein Info for RR42_RS01860 in Cupriavidus basilensis FW507-4G11

Annotation: amidophosphoribosyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 243 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF18912: DZR_2" amino acids 8 to 66 (59 residues), 29.2 bits, see alignment E=6.4e-11 PF00156: Pribosyltran" amino acids 148 to 238 (91 residues), 34.8 bits, see alignment E=9.9e-13

Best Hits

KEGG orthology group: None (inferred from 60% identity to reu:Reut_A0311)

Predicted SEED Role

"Competence protein F homolog, phosphoribosyltransferase domain; protein YhgH required for utilization of DNA as sole source of carbon and energy"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y4N3 at UniProt or InterPro

Protein Sequence (243 amino acids)

>RR42_RS01860 amidophosphoribosyltransferase (Cupriavidus basilensis FW507-4G11)
MRHHARRLLRTLLPAACALCGTVQDETVCAGCALELLAPLPRCRCCARPLGRSAGPGAAS
LCAQCRYEPPPFDDALVLGDYARPQDGLVLALKFGGVLPLADWLGGELARRWQAESGRSG
LALPDVLAPIPLSAQRLAERGFNQSWEIARPLARRLGVRAAPTLLARLRDTPAQATLDLP
ARQANLQDAFGLGASHDVAGQHVGLVDDVMTSGATLGEAARVLKANGAARVTLVVALRTP
GPA