Protein Info for RR42_RS00415 in Cupriavidus basilensis FW507-4G11

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 280 transmembrane" amino acids 27 to 45 (19 residues), see Phobius details amino acids 57 to 77 (21 residues), see Phobius details amino acids 83 to 103 (21 residues), see Phobius details amino acids 110 to 130 (21 residues), see Phobius details amino acids 136 to 155 (20 residues), see Phobius details amino acids 165 to 186 (22 residues), see Phobius details amino acids 198 to 216 (19 residues), see Phobius details amino acids 226 to 247 (22 residues), see Phobius details amino acids 253 to 269 (17 residues), see Phobius details PF00892: EamA" amino acids 4 to 126 (123 residues), 55.1 bits, see alignment E=5e-19 amino acids 137 to 268 (132 residues), 71.1 bits, see alignment E=5.7e-24

Best Hits

KEGG orthology group: None (inferred from 80% identity to reh:H16_A0077)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4XYH0 at UniProt or InterPro

Protein Sequence (280 amino acids)

>RR42_RS00415 ABC transporter permease (Cupriavidus basilensis FW507-4G11)
MLTASAPLIWGSTYLVTSQWLPPGQPLLSGVIRALPAGLAMLAWGRQLPRGGWWWKAAVL
GVLNIGLFQAMLFIAAYRLPGGVAATVGAIQPLLVAVLAWLLLGARPRPATWLAGLGGIG
GVALLVLGPAARLDGVGVAAAAAGAVSMALGTVLAKRWRAPVSPLVLTAWQLTAGALFLL
PFALAFETLPARLTVPNVLGYLWLCVAGAGVSYALWFRGIGRLPTAAVSALGLLSPVSAT
ALGFLVLGQRLSPAQMAGALLVLASVWLGQRAPKAAPAAA