Protein Info for RALBFv3_RS21640 in Ralstonia solanacearum IBSBF1503

Annotation: GGDEF domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 580 PF00989: PAS" amino acids 1 to 44 (44 residues), 23.5 bits, see alignment 1.2e-08 PF13188: PAS_8" amino acids 2 to 57 (56 residues), 28.7 bits, see alignment 2.3e-10 PF08448: PAS_4" amino acids 3 to 106 (104 residues), 44.4 bits, see alignment E=4.5e-15 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 137 to 298 (162 residues), 158 bits, see alignment E=1.7e-50 PF00990: GGDEF" amino acids 140 to 296 (157 residues), 177.7 bits, see alignment E=4e-56 PF00563: EAL" amino acids 318 to 551 (234 residues), 251.7 bits, see alignment E=1.6e-78

Best Hits

KEGG orthology group: None (inferred from 95% identity to rso:RS00808)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (580 amino acids)

>RALBFv3_RS21640 GGDEF domain-containing protein (Ralstonia solanacearum IBSBF1503)
MVNALTEGLLVCDAQRRVTYANPSAARLLGVSLDTLVGLRLPEAVGAAIDEFDTPIRDID
WPDGDVLADGRPQLNQIFGLRCLDGRTVWVSTNWTPLYAEAGEPATASPAGRHAQPYAVL
VSLVDITQIREAQQRIRHLATHDTLTGLLNRCALEDRLEHALALARRNGTRVSVMFLDLD
RFKNINDTLGHQFGDQLLREVAARLQACAREADTVARLGGDEFVVMLESLDSMGTRRVAE
RILAAIGAPFHIEGQELFVGVSIGIAVAPHDGDDPNTLLRKADAAMYLAKERGRNNFQTF
TSDLDDRVSRRFRIESGLRRASDRNEFYANYQPRVDVRTGRIVGVEALIRWNSADFGRLM
PGQFIQDAEETGLIVEIDRWILRAACDQLARWRRIGLPHLRMSINLSGQAFSSGQLSGMV
RGALTNSGLPGEAVELEMTEGILIRDDPSLHALLTELRALGVSLALDDFGTGYSSLSYLH
RFPIDTLKIDRSFVQDLPHVAERAAITRAIIMMAQAMGMKTVAEGVETAGQLEFLREIGC
DEYQGYLLTRPLEPAAMHDLVREHERRHGAVRPGFLPLSR