Protein Info for RALBFv3_RS15680 in Ralstonia solanacearum IBSBF1503

Annotation: translation initiation factor IF-2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 968 PF04760: IF2_N" amino acids 1 to 52 (52 residues), 35.6 bits, see alignment 2.3e-12 amino acids 390 to 440 (51 residues), 59 bits, see alignment 1.1e-19 PF08364: IF2_assoc" amino acids 62 to 100 (39 residues), 52.6 bits, see alignment (E = 1.4e-17) TIGR00487: translation initiation factor IF-2" amino acids 385 to 968 (584 residues), 877.7 bits, see alignment E=4.5e-268 TIGR00231: small GTP-binding protein domain" amino acids 470 to 627 (158 residues), 114.8 bits, see alignment E=3.4e-37 PF01926: MMR_HSR1" amino acids 473 to 578 (106 residues), 40.9 bits, see alignment E=6.9e-14 PF00009: GTP_EFTU" amino acids 473 to 628 (156 residues), 131.7 bits, see alignment E=8.4e-42 PF00071: Ras" amino acids 474 to 629 (156 residues), 25.8 bits, see alignment E=2.6e-09 PF11987: IF-2" amino acids 744 to 858 (115 residues), 149.4 bits, see alignment E=1.4e-47

Best Hits

Swiss-Prot: 81% identical to IF2_CUPNJ: Translation initiation factor IF-2 (infB) from Cupriavidus necator (strain JMP 134 / LMG 1197)

KEGG orthology group: K02519, translation initiation factor IF-2 (inferred from 75% identity to bmu:Bmul_1755)

Predicted SEED Role

"Translation initiation factor 2" in subsystem NusA-TFII Cluster or Translation initiation factors eukaryotic and archaeal or Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (968 amino acids)

>RALBFv3_RS15680 translation initiation factor IF-2 (Ralstonia solanacearum IBSBF1503)
MASTTVAQLAGELNRSAAALLEQLQAAGVQKATPEDVITESDKTRLLDYLKRAHGSAEDG
ARKKITLTKRETSEIRQADATGKTRTVQVEVRKKRVLIKRDEPGAAPAEAEAEATAASAA
PVVDAEEVARREEEQRRQAELLARQEAELKARQEAMEREEAERRARQEAAEAEQRRQAEL
AAKKAEEEAAAARAAAEASDEAPRRKAEEDAARLASEREAAQKAAEEARARADKIKAEED
AARKRREAAEAEARAIREMMSAPARVLKTPAERKAEEKKAEQSGTLHKPVKPAGEARPAA
PAAKKAAVPAATPAAAPAGDKKGGRGGKSGGWQDDSRGNKRGGLKTRGDTGGGGDGWRAG
SKGGRNRHGDDNRNAFQAPTEPVVREVHVPETISVADLAHKMAVKAAEVIKQMMKLGQMV
TINQVLDQETAMIVVEEMGHQAVAAKLDDPEALLVEGVQEQQNVEAETRPPVVTVMGHVD
HGKTSLLDYIRRAKVAAGEAGGITQHIGAYHVETQRGVITFLDTPGHEAFTAMRARGAKA
TDIVILVVAADDGVMPQTKEAIAHAKAAGVPIVVAINKIDKPDANPDRVKQELVSESVIP
EEYGGESPFVSVSAKTGQGIDDLLENVLLQAEVLELKAPVSAPAKGLVVEAQLDKGKGSI
ATVLVQSGTLKRGDVVLAGTAYGRVRAMLDENGKPAKEAGPSIPVEIQGLSEVPGAGEEV
IVLPDERKAREIALFRQGKFRDVKLARQQAAKLETMLEQMSEGEVKTLPLIIKADVQGSQ
EALVHALNKLSTGEVRVQVVHGAVGGISESDVNLATASKAVIIGFNTRADAGARKLAEHQ
GIDIRYYNIIYDAVDEVKAAMSGMLSPEKKEETTGTVEVRQVFHVPKVGAVAGCMVLDGI
VKRSSLVRVLRDNVVIFSGELESLKRFKDDVKEVKQGFECGLSIKNFNDVKEGDQLEIYE
ITEVARTL