Protein Info for RALBFv3_RS14925 in Ralstonia solanacearum IBSBF1503

Annotation: LysR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 297 PF00126: HTH_1" amino acids 5 to 63 (59 residues), 65.5 bits, see alignment E=3.5e-22 PF03466: LysR_substrate" amino acids 89 to 293 (205 residues), 141.5 bits, see alignment E=2.6e-45

Best Hits

Swiss-Prot: 45% identical to YAFC_ECOLI: Uncharacterized HTH-type transcriptional regulator YafC (yafC) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 99% identity to rsc:RCFBP_20281)

Predicted SEED Role

"Transcriptional regulator, LysR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (297 amino acids)

>RALBFv3_RS14925 LysR family transcriptional regulator (Ralstonia solanacearum IBSBF1503)
MKTTLEELLAFRTVVDTGSVTAAAEQLGQTVSGVSRALRRLEEKLETTLLSRTTRRLALT
DEGAAFLAHARGILAAVDEAEELIALRRQQPAGRLRVNAAMPFMLHVIAPLVADFRAQYP
QIELELNTSDRIIDLLEEDTDVAIRIGTLRDSTLRARRLGTRRLRVLASPAYLKAHGRPR
TIDDLRHHTLLGFVQPESLNHWPLRGPHGDRLRIVPTLKASSGETLRQLALQGAGLVCLA
DFMTAADRRAGDLVQVLPDATVEILQPIHAVYYRNTQLASRIACFLDFLETRLAQAE