Protein Info for RALBFv3_RS14365 in Ralstonia solanacearum IBSBF1503

Annotation: GTP 3',8-cyclase MoaA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 373 TIGR02666: molybdenum cofactor biosynthesis protein A" amino acids 35 to 373 (339 residues), 389.5 bits, see alignment E=6e-121 PF04055: Radical_SAM" amino acids 48 to 217 (170 residues), 118.5 bits, see alignment E=5.3e-38 PF13353: Fer4_12" amino acids 53 to 159 (107 residues), 27.5 bits, see alignment E=5.5e-10 PF06463: Mob_synth_C" amino acids 225 to 351 (127 residues), 132.3 bits, see alignment E=1.6e-42

Best Hits

Swiss-Prot: 90% identical to MOAA_RALSO: GTP 3',8-cyclase (moaA) from Ralstonia solanacearum (strain GMI1000)

KEGG orthology group: K03639, molybdenum cofactor biosynthesis protein (inferred from 99% identity to rsc:RCFBP_20441)

Predicted SEED Role

"Molybdenum cofactor biosynthesis protein MoaA" in subsystem Molybdenum cofactor biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (373 amino acids)

>RALBFv3_RS14365 GTP 3',8-cyclase MoaA (Ralstonia solanacearum IBSBF1503)
MTETVIPLYDLRDGQHHRATVPAVPDTLVPAQGWLTDTRGRRLHDLRISVTDRCNFRCVY
CMPKDVFDKDYRFLRHSELLSFEEIERMVRLFIEHGVEKIRLTGGEPLLRKDIERLVEML
ARLTTRDGKPLDLTLTTNGALLARKAQSLKDAGLKRVTVSLDAIDDATFRRMNDVDFAVG
EVLHGIEVAQNVGLSPLKLNMVVKRGDNDDQIVPMARHFRGSGIILRFIEYMDVGATNHW
EMTSVVPSAEVIRRLSAAFALEPLSANYTGETAERWRYADGAGEIGVISSVTQAFCHACT
RARLSTEGKLYLCLFAVEGFDLRALLRGGATDLELSNTIRNIWQARTDRYSELRSSGQVD
AADRRIEMSYIGG