Protein Info for RALBFv3_RS14290 in Ralstonia solanacearum IBSBF1503

Annotation: Fe-S protein assembly chaperone HscA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 621 TIGR01991: Fe-S protein assembly chaperone HscA" amino acids 21 to 619 (599 residues), 950.1 bits, see alignment E=2.5e-290 PF00012: HSP70" amino acids 21 to 603 (583 residues), 610.4 bits, see alignment E=3e-187 PF06723: MreB_Mbl" amino acids 121 to 376 (256 residues), 55.5 bits, see alignment E=4.2e-19

Best Hits

Swiss-Prot: 96% identical to HSCA_RALSO: Chaperone protein HscA homolog (hscA) from Ralstonia solanacearum (strain GMI1000)

KEGG orthology group: K04044, molecular chaperone HscA (inferred from 99% identity to rsc:RCFBP_20456)

Predicted SEED Role

"Chaperone protein HscA" in subsystem Protein chaperones

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (621 amino acids)

>RALBFv3_RS14290 Fe-S protein assembly chaperone HscA (Ralstonia solanacearum IBSBF1503)
MALLQISEPGESPAPHQRRLAVGIDLGTTNSLVASVRSSVPEVLPDDQGRPLLPSVVRYL
PAGGTQIGYKAQAEAVRDPKNTILSVKRFMGRGLKDVAHIENTPYDFVDAPGMVQLKTVA
GVKSPVEVSAEILATLRQRAEDTLGDELVGAVITVPAYFDDAQRQATKDAARLAGLNVLR
LLNEPTAAAIAYGLDNAAEGVYAVYDLGGGTFDISILRLTKGVFEVMSTGGDSALGGDDF
DQRIACWIVERAGLQPLSAEDTRLLLNKARAAKEWLSSADSTEVDAVLSTGETVHLVLSA
ETFAELTATLVQKTLAPVRRALRDAGVTVDEVQGVVLVGGATRMPVIRRAVAQLFGRTPL
TNLDPDQVVAIGAAMQANLLAGNRAAGDDWLLLDVIPLSLGVETMGGLVEKIIPRNSTIP
VARAQEFTTFKDGQTAMAIHVLQGERELASDCRSLARFELRGIPPMVAGAARIRVTYQVD
ADGLLSVSARETVSGVEASITVKPSYGLGDDDIARMLQEGFQSAEEDMRRRALAEERVEG
ERLLEALSHALDADGDLLSADERSAIDALVAALRVTLQGEDHRAIKDAVDALSHGTDEFA
ARRMDRGIRAALAGKRIEELG