Protein Info for RALBFv3_RS13965 in Ralstonia solanacearum IBSBF1503

Annotation: metalloprotease PmbA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 457 transmembrane" amino acids 253 to 272 (20 residues), see Phobius details PF01523: PmbA_TldD_1st" amino acids 43 to 103 (61 residues), 48.1 bits, see alignment E=1.6e-16 PF19290: PmbA_TldD_2nd" amino acids 130 to 237 (108 residues), 68.6 bits, see alignment E=9.9e-23 PF19289: PmbA_TldD_3rd" amino acids 244 to 456 (213 residues), 237.7 bits, see alignment E=1.3e-74

Best Hits

KEGG orthology group: K03592, PmbA protein (inferred from 100% identity to rsc:RCFBP_20523)

Predicted SEED Role

"TldE protein, part of TldE/TldD proteolytic complex"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (457 amino acids)

>RALBFv3_RS13965 metalloprotease PmbA (Ralstonia solanacearum IBSBF1503)
MTDTLDSKTDSVFAYRREQLEEMARDVLRVARELGATDAATEISEGQGLSVTVRKGEIET
IEQNRDKVVGVTVMLGKKRGNASTSDFSPAALRSTVEAAYNIARFTADDDCAGLAEEELL
EQHPRDLSLYHPWTLDAEAAVEIARASEAAALAVSPKIRNSDGASVSAQHSHFVLATSRG
FLGGYPYSRHFISCAPIAGSGRHMQRDDWYSSKRSPKDLAAPEAIGQYAAERALARLSAR
RLTTRKCPVLFEAPLAAGLLGAFVQAVSGGALYRKSTFLLDALGKEIFAPHVQIKEDPHV
PSGMGSAPFDEEGVRTRRRDVVKDGVVEGYFLSTYSARKLGMQTTGNAGGSHNLTLFSDR
TQPEDDFAGMLRRMGTGLLVTELMGQGVNYVTGDYSRGASGYWVENGVIQYPVEEITIAG
SLPDMFRQIVAIGADALVRGTKETGSILIEQMTIAGE