Protein Info for RALBFv3_RS10935 in Ralstonia solanacearum IBSBF1503

Annotation: SAM-dependent methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 313 PF13489: Methyltransf_23" amino acids 36 to 172 (137 residues), 44.8 bits, see alignment E=2.8e-15 PF13847: Methyltransf_31" amino acids 50 to 165 (116 residues), 53.2 bits, see alignment E=7.1e-18 PF13649: Methyltransf_25" amino acids 52 to 157 (106 residues), 61.2 bits, see alignment E=3.2e-20 PF08241: Methyltransf_11" amino acids 52 to 161 (110 residues), 75.7 bits, see alignment E=9.3e-25 PF08242: Methyltransf_12" amino acids 52 to 159 (108 residues), 43.2 bits, see alignment E=1.4e-14

Best Hits

Swiss-Prot: 40% identical to BIOC_LEGPH: Malonyl-[acyl-carrier protein] O-methyltransferase (bioC) from Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)

KEGG orthology group: K02169, biotin synthesis protein BioC (inferred from 98% identity to rsc:RCFBP_21127)

Predicted SEED Role

"Biotin synthesis protein BioC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (313 amino acids)

>RALBFv3_RS10935 SAM-dependent methyltransferase (Ralstonia solanacearum IBSBF1503)
MPDPVLARPDALRRAFDRRAARFAAVDFLLREVGQRMQDRLSYIKLTPARALDLGCGLGQ
GLAVLRAQYPDAQICGLDWSAAMLARARQLDPQRSDAGWLGRLLKKRPVFDFAQADFRAL
PFADASFDLLWSNLALHWDPSPHQIFPEWHRVTAEGGLLMFSLFGPDTLRELRSALAGID
TRVHTLRFVDMHDIGDMLVHSRWSTPVMDMEQITITYESPQALLADVHLLGGMAGLEDGD
GHALSGPGLHTPRWRQHLFDALDAQRNPDGLIPLTFEVVYGHAWKLAPTARQALDEQGRT
MVPIDRIGRKPRA