Protein Info for RALBFv3_RS10790 in Ralstonia solanacearum IBSBF1503

Annotation: sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 665 transmembrane" amino acids 44 to 68 (25 residues), see Phobius details amino acids 340 to 361 (22 residues), see Phobius details PF02743: dCache_1" amino acids 73 to 257 (185 residues), 46.9 bits, see alignment E=3.8e-16 PF00512: HisKA" amino acids 433 to 495 (63 residues), 28.3 bits, see alignment E=2.3e-10 PF02518: HATPase_c" amino acids 543 to 654 (112 residues), 78.4 bits, see alignment E=8.2e-26

Best Hits

KEGG orthology group: K10125, two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC: 2.7.13.3] (inferred from 98% identity to rsc:RCFBP_21156)

Predicted SEED Role

"Signal transduction histidine kinase regulating C4-dicarboxylate transport system (EC 2.7.13.3)" (EC 2.7.13.3)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (665 amino acids)

>RALBFv3_RS10790 sensor histidine kinase (Ralstonia solanacearum IBSBF1503)
MRHGTERLMVDAAPEGTASPSAVRLPPMSEPDFPFSSTSPRRGFGWLVAAGLLAVMALVC
TTTFVVTWNRGLSQAQQAAGARVDRYAANLKSTLDRYEYLPALVALHPFIHDLLAHPTPD
NVARANRYLREVNDRARATATYVIAPSGLALAASNYNLPDSFVGAEYLFRPYFQQAAAGH
IGRFYAIGITREEPGYYISQPVMRDGRVIGVTVVKLNLEWFGRASHDASEPVMVADENGV
IFLSSVPAWQYRTVEPFTPELQAQLQATRQYYRKQITSLPLQPEMPAFLKLVGRMPDGAR
LVRVGDRINAPRYLLVSRELVEPDWQLMYLTPVDPVMGAARSATIAAAFAFAFVCLLLFY
WRQRRLRLMEMLGSRRLLEAAYDQLERRVEDRTADLMATNEQLQHEIVDRTRAEAELRAT
QDELVQASKLAALGQMAAGITHELNQPLAALRTFSDNTRILLERGQHGAAADNLRAIADL
TERMGKITAQLKLFAGRSRRKHIDVQVRVALDHVLALLRPRLAEVEVVLHWRLPEAECVV
RADELKLEQVLINLIGNALDAIAGNDLSRPGRIDIDIGPADGVPAQLCIVVRDNGPGISA
DAMPHLFEPFFTTKEIGQGLGLGLAISTSIARDFGGSLSAANLPDGGAQFTLSMVRAEVA
PAAMS