Protein Info for RALBFv3_RS06280 in Ralstonia solanacearum IBSBF1503

Annotation: putative lipid II flippase FtsW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 413 transmembrane" amino acids 44 to 65 (22 residues), see Phobius details amino acids 81 to 101 (21 residues), see Phobius details amino acids 113 to 130 (18 residues), see Phobius details amino acids 149 to 166 (18 residues), see Phobius details amino acids 178 to 195 (18 residues), see Phobius details amino acids 201 to 218 (18 residues), see Phobius details amino acids 224 to 243 (20 residues), see Phobius details amino acids 301 to 325 (25 residues), see Phobius details amino acids 346 to 367 (22 residues), see Phobius details amino acids 379 to 400 (22 residues), see Phobius details TIGR02614: cell division protein FtsW" amino acids 42 to 403 (362 residues), 411.3 bits, see alignment E=1.7e-127 PF01098: FTSW_RODA_SPOVE" amino acids 44 to 405 (362 residues), 353.9 bits, see alignment E=4.7e-110

Best Hits

Swiss-Prot: 77% identical to FTSW_BURTA: Probable peptidoglycan glycosyltransferase FtsW (ftsW) from Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)

KEGG orthology group: K03588, cell division protein FtsW (inferred from 98% identity to rso:RSc2845)

Predicted SEED Role

"Cell division protein FtsW" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (413 amino acids)

>RALBFv3_RS06280 putative lipid II flippase FtsW (Ralstonia solanacearum IBSBF1503)
MSDTQIKRSGFIGATIGNAWEGLRDAVSGVKPTRSKMMEYDQPLLWVSIVLLGLGLVMVY
SASIALPDSPKYANYTNGHFLIRHAFSLLIGVIGAVVAFQIPVKFWDKYAPKLFIIALVL
LVVVLIPHVGKGVNGARRWLPLGIMNFQPSELMKLAVVLYAANYTVRKQDWMQSVRKGFL
PMGVAVAFVGSLLLLEPDMGAFLVIAAVAMGILFLGGVNGKLFGGLVLTAVSTFSLLILM
SPWRRERIFAYLNPWQEEYAQGKAYQLTHSLIAFGRGEWTGVGLGGSIEKLHYLPEAHTD
FILAVIGEELGFIGVLIVILLFYWMVRRAFEIGRTALQLDRTFSGLVAKGLGIWIGWQAF
INMGVNLGLLPTKGLTLPMVSYGGSGILMNCMAIALLLRIDYENRVLMRGGKV