Protein Info for RALBFv3_RS05615 in Ralstonia solanacearum IBSBF1503

Annotation: drug/metabolite DMT transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 314 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 35 to 56 (22 residues), see Phobius details amino acids 65 to 87 (23 residues), see Phobius details amino acids 93 to 114 (22 residues), see Phobius details amino acids 121 to 140 (20 residues), see Phobius details amino acids 159 to 177 (19 residues), see Phobius details amino acids 187 to 204 (18 residues), see Phobius details amino acids 216 to 235 (20 residues), see Phobius details amino acids 244 to 265 (22 residues), see Phobius details amino acids 271 to 290 (20 residues), see Phobius details PF00892: EamA" amino acids 162 to 286 (125 residues), 34.2 bits, see alignment E=1.4e-12

Best Hits

Swiss-Prot: 62% identical to YDDG_ECOLI: Aromatic amino acid exporter YddG (yddG) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 98% identity to rsc:RCFBP_10755)

MetaCyc: 62% identical to amino acid exporter YddG (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-265

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (314 amino acids)

>RALBFv3_RS05615 drug/metabolite DMT transporter permease (Ralstonia solanacearum IBSBF1503)
MQNKRKATLIGLIAVLLWSSIVGLIRGVSQSLGAVGGAAMMYSVASVLLWSSIGFIRLKD
VPRRYLVWGSLLFVSYELCLSLSIGYANSSRQAIEVGMVNYLWPTFTMLSAIAFNKQKSN
FLIVPGFLVAILGICLVLGGDQGLDIAGMAANIRDNPLSYGLAFSGALIWAAYCTVTSRI
AEGKNGITLFFMLTALALWIKYFATGGGAMHWSYEAIIYLALAASAMGFGYAAWNVGILH
GNVTVLAGASYFIPVFSAALAATLLHTPLSFAFWRGASMVCAGSILCWLATRGQRSREPA
APSRSQPRERAHGQ