Protein Info for RALBFv3_RS04645 in Ralstonia solanacearum IBSBF1503

Annotation: chloride channel protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 transmembrane" amino acids 20 to 45 (26 residues), see Phobius details amino acids 65 to 84 (20 residues), see Phobius details amino acids 120 to 132 (13 residues), see Phobius details amino acids 138 to 153 (16 residues), see Phobius details amino acids 163 to 191 (29 residues), see Phobius details amino acids 198 to 217 (20 residues), see Phobius details amino acids 223 to 249 (27 residues), see Phobius details amino acids 269 to 287 (19 residues), see Phobius details amino acids 307 to 328 (22 residues), see Phobius details amino acids 334 to 354 (21 residues), see Phobius details amino acids 361 to 388 (28 residues), see Phobius details amino acids 394 to 414 (21 residues), see Phobius details PF00654: Voltage_CLC" amino acids 76 to 408 (333 residues), 267.2 bits, see alignment E=2.4e-83 PF00571: CBS" amino acids 443 to 495 (53 residues), 21.7 bits, see alignment 2.1e-08 amino acids 514 to 561 (48 residues), 25.6 bits, see alignment 1.2e-09

Best Hits

KEGG orthology group: None (inferred from 99% identity to rsc:RCFBP_10995)

Predicted SEED Role

"Chloride channel protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (600 amino acids)

>RALBFv3_RS04645 chloride channel protein (Ralstonia solanacearum IBSBF1503)
MQAHTLRRDFATDTTLFRTAALAVVIAAFATLAAVVLLDLIRFFTNLFFFQALSLADRSP
AGNTLGLWVIAVPVLGGLIVGLMARFGSDKIRGHGIPEAIEAILFGKSRMSPKVAVLKPL
SSGIVIGSGGPFGAEGPIIMTGGAIGSLLAQCFKLTAAERKTLLVAGAAAGMTAVFGTPV
AALLLAVELLLFEWRPRSMLPVAIACAVAGFLRVLVLEPGPLFPLATAPATLPALGSCLV
AGLLCGALSRSLSMALYKTEDLFARLPIHWMWWPALGGLAVGIGGYFEPHALGVGYDVIG
DLLHNHLAIRVALALLVVKALIWVIALGSGTSGGVLAPLLMMGAGLGVMLGPVLPGGDPG
LWPLVCMAATLAGVLGAPLTAIVFAFGLTHDVNAILPVLLAVSVAYGFVVLTMPRSIMTE
KIARRGFHIYREYAVDPLERHAVDEVMTRAVQTIDAHASVAGILAERFGPTQAHRAFPVV
RDGVLVGMLDRDALLAGHARSAATIADLFGANAPVMALPGETCRIVATRLAVHGLERLPV
VADTQSRRLVGIVSRSDLVKLSLAFFDEEQRRERFRRTPLAGARTQLELRRRRARRTPSA