Protein Info for Psyr_4946 in Pseudomonas syringae pv. syringae B728a

Annotation: Oxidoreductase alpha (molybdopterin) subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01701: oxidoreductase alpha (molybdopterin) subunit
  • amino acids 22 to 770 (749 residues), 953 bits, E=5.4e-291
• PF00384: Molybdopterin
  • amino acids 118 to 499 (382 residues), 97.3 bits, E=5.1e-32

Best Hits

KEGG orthology group: K00123, formate dehydrogenase, alpha subunit [EC: 1.2.1.2] (inferred from 100% identity to psb:Psyr_4946)

Predicted SEED Role

"Putative formate dehydrogenase oxidoreductase protein" in subsystem Formate hydrogenase

MetaCyc Pathways

• formate oxidation to CO₂ (1/1 steps found)
• purine nucleobases degradation II (anaerobic) (16/24 steps found)
• oxalate degradation VI (1/4 steps found)
• oxalate degradation III (1/5 steps found)
• superpathway of C1 compounds oxidation to CO₂ (5/12 steps found)
• purine nucleobases degradation I (anaerobic) (6/15 steps found)

KEGG Metabolic Maps

• Glyoxylate and dicarboxylate metabolism
• Methane metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.2.1.2

Use Curated BLAST to search for 1.2.1.2

Sequence Analysis Tools

See Q4ZLJ9 at UniProt or InterPro

Protein Sequence (778 amino acids)

>Psyr_4946 Oxidoreductase alpha (molybdopterin) subunit (Pseudomonas syringae pv. syringae B728a)
MSTHHQADKTPTPRYKPYKGAAGGWGALISVTQHWLGSDNALKNLRMMLKTNQNGGFDCP
GCAWGDSPESGMVKFCENGAKAVNWEATKRRVDPAFFARYSVSSLMEQSDYWLEYQGRLT
EPMSYDAETDRYKPISWDSAFALIAKHLKNLPSPNMAEFYTSGRASNEAAYLYQLFVRAY
GTNNFPDCSNMCHEASGVALSQSVGVGKGTVTFEDFEHADAIFVLGQNPGTNHPRMLEPL
REAVQRGAQVVCVNPLKERGLERFQHPQHPVEMLTNGDRPTNTAYFRPALGGDMALLRGM
AKFLLQWEREAQANNAPSVFDHAFLNEHTEGVLEYLAAIDDTSWDAIVEQSGLPLSDIEQ
SARMYAKGKNVIMCWAMGITQHRHSVPTIQEIANLMLLRGNIGRPGAGLCPVRGHSNVQG
DRTMGINERPPVFLLDALEKRFQFKVPRENGHNVVEAIHAMAEGRAKVFIALGGNFAQAT
PDSHRTAEALSKCDLTVQISTKLNRSHLFHGKDALILPCFGRTDIDIQANGPQAVTVEDS
FSMVHASNGQLKPSSKQMRSEPAIIAGIANATLGKTPVDWLWLVEDYNRIRDLIADTIPG
FKDFNERVKHPGGFYLGNAAGARRWNTASTRANFKSNALPLTLINEHVSSTGQIPDLIMQ
SMRSHDQYNTTIYGLDDRYRGVKGQRDVLFVNEADIIRLGFQPGQKADLISIWSDNRERR
VKGFTLLPFDIPAGQAAAYYPEVNPLVPLESVGDGSSTPTSKFVAIRLERSAESARIL