Protein Info for Psyr_4771 in Pseudomonas syringae pv. syringae B728a

Annotation: Peptide methionine sulfoxide reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00401: peptide-methionine (S)-S-oxide reductase
  • amino acids 51 to 204 (154 residues), 214.5 bits, E=4.6e-68
• PF01625: PMSR
  • amino acids 52 to 204 (153 residues), 209.3 bits, E=1.8e-66

Best Hits

Swiss-Prot: 100% identical to MSRA_PSEU2: Peptide methionine sulfoxide reductase MsrA (msrA) from Pseudomonas syringae pv. syringae (strain B728a)

KEGG orthology group: K07304, peptide-methionine (S)-S-oxide reductase [EC: 1.8.4.11] (inferred from 100% identity to psb:Psyr_4771)

MetaCyc: 60% identical to methionine sulfoxide reductase A (Escherichia coli K-12 substr. MG1655)
L-methionine (S)-S-oxide reductase. [EC: 1.8.4.13]; Peptide-methionine (S)-S-oxide reductase. [EC: 1.8.4.13, 1.8.4.11]

Predicted SEED Role

"Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11)" (EC 1.8.4.11)

KEGG Metabolic Maps

• Methionine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.8.4.11 or 1.8.4.13

Sequence Analysis Tools

See Q4ZM24 at UniProt or InterPro

Protein Sequence (215 amino acids)

>Psyr_4771 Peptide methionine sulfoxide reductase (Pseudomonas syringae pv. syringae B728a)
MTLRSEILVNKNVLPTAEQALPGRETPMALPEFHFVNGNPLLGPFSSNVEFAIFGMGCFW
GAERRLWQQEGVVSTVAGYAGGFTPNPTYEEVCSGLTGHTEVVLVVYEPAKISYEELLKV
FWEVHNPTQGMRQGNDIGTQYRSVIYCTTPEQLDAAKASAETFQAQLNKAGKGTITTEIE
QAPTVYFAEAYHQQYLAKNPQGYCGLGGTGVCMPA