Protein Info for Psyr_4619 in Pseudomonas syringae pv. syringae B728a

Annotation: multi-sensor signal transduction histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 670 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 281 to 302 (22 residues), see Phobius details PF00497: SBP_bac_3" amino acids 52 to 268 (217 residues), 92.3 bits, see alignment E=1.2e-29 TIGR00229: PAS domain S-box protein" amino acids 337 to 449 (113 residues), 47.1 bits, see alignment E=1.3e-16 PF00989: PAS" amino acids 338 to 442 (105 residues), 33.7 bits, see alignment E=1.2e-11 PF08448: PAS_4" amino acids 339 to 447 (109 residues), 36.7 bits, see alignment E=1.6e-12 PF13426: PAS_9" amino acids 344 to 444 (101 residues), 41 bits, see alignment E=6.9e-14 PF07730: HisKA_3" amino acids 466 to 532 (67 residues), 51.1 bits, see alignment E=5.6e-17 PF02518: HATPase_c" amino acids 573 to 662 (90 residues), 43.6 bits, see alignment E=1.3e-14

Best Hits

KEGG orthology group: None (inferred from 100% identity to psb:Psyr_4619)

Predicted SEED Role

"Probable two-component sensor, near polyamine transporter" in subsystem Polyamine Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZMH3 at UniProt or InterPro

Protein Sequence (670 amino acids)

>Psyr_4619 multi-sensor signal transduction histidine kinase (Pseudomonas syringae pv. syringae B728a)
MIRLLRTGFIGCLALLLMAQMANTQADEPQTPAVAQLSAAQRNWLDQHGPLRVGLVLRAP
YAQFDQRLQQLSGANVDLMNALAATLPVDLLWRNFPDQSALENALAKGEIDVAPGLMQTP
AGLRLWLFSDPYLRVSQLLIGERDGSTAVDLEKLDSLSRVAVRMPSTTADYLRSNFAHLN
LQGVPLERQALQLLLSQQARYAVVDEAQLSRLLREPEFAGLAVVGDIGLPQLLRVASRRD
MPELAAIVSEALRAIPAKELEQLHARWMPLTPSHFIESTKLWKNLCILLLVMLLACFAIV
IWQRRQQQALEQELLAAREELARRVEEEEALRLAQFSIDQSTVGILWVNWDSRVRYANRA
AESMLGYAPGQVVERPLIDFEPGLHMDRWLNLWKSARSSEDSPQVFETHCLRADGSLLPV
DVSLSFLRFRDAEYLVVFLTDVSERRRAHDLLRELSAHLESVREEEKAHIAREVHDELGQ
MLTVLKLETSMCELAYADLDPGLSERLDSMKRLIAQLFQLVRDVATALRPPILDAGIASA
IEWQARRFEARTQIPCLVQVPDNLPALSDARATGMFRILQEALTNVMRHARAHTVEISLT
LQDGMMCMSIADDGQGFVIESGRAVSFGLVGMRERVLMLGGRLELDSEVGEGTTLRAYIP
LDTLAQERRQ